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Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients

Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients

This study evaluated the safety and volume reduction of ultrasonography (US)-guided radiofrequency ablation (RFA) for benign thyroid nodules, and the factors affecting the results obtained. A total of
302 benign thyroid nodules in 236 euthyroid patients underwent RFA between June 2002 and January 2005. RFA was carried out using an internally cooled electrode under local anesthesia. The volume-reduction ratio (VRR) was assessed by US and safety was determined by observing the complications during the followup period (1–41 months). The correlation between the VRR and several
factors (patient age, volume and composition of the index nodule) was evaluated. The volume of index
nodules was 0.11–95.61 ml (mean, 6.13±9.59 ml). After ablation, the volume of index nodules decreased to
0.00–26.07 ml (mean, 1.12±2.92 ml) and the VRR was 12.52–100% (mean, 84.11±14.93%) at the last follow-up.
A VRR greater than 50% was observed in 91.06% of nodules, and 27.81% of index nodules disappeared.

Conclusion

Radiofrequency ablation (RFA) is a minimally invasive technique that has been used to treat benign and malignant tumors [21–24]. In the thyroid gland, RFA has been applied to a recurrent thyroid cancer [23] and benign thyroid nodules [25]. This study evaluated the safety and effectiveness of RFA at reducing volume in benign thyroid nodules. In conclusion, RFA is a safe modality effective at reducing volume in benign thyroid nodules. Thyroid nodule RFA appears safe and imaging follow-up confirms volume reduction.

Citation

Jeong, W. K., Baek, J. H., Rhim, H., Kim, Y. S., Kwak, M. S., Jeong, H. J., & Lee, D. (2008). Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients. European Radiology, 18(6), 1244–1250. doi:10.1007/s00330-008-0880-6

Key Words

Radiofrequency ablation, Thyroid nodule, Thyroid ultrasound Intervention

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