nsPFA is the abreviation for Nanosecond Pulsed Field Ablation (nsPFA)
It is also referred to as CellFX.
It is indicated for ablation of soft tissue in percutaneous, and intraoperative surgical procedures, such as thyroid nodules.
nsPFA creates a high volutage DC electric field in very short-duration pulses. It penetrates the cell membrane and disrupts internal cellular function, leading to regulated cell death. nsPFA eliminates targeted cells while sparing adjacent noncellular tissue. It is a nonthermal treatment because the total energy delivered is low.
Unlike thermal (heat/cold) modalities, nsPFA directly impacts cellular structures while sparing noncellular tissue