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diagnosis and management of thyroid nodules: a review

Thyroid nodules are common, being detected in up to 65% of the general population. This is likely due to the increased use of diagnostic imaging for purposes unrelated to the thyroid.

Durante C, Grani G, Lamartina L, Filetti S, Mandel SJ, Cooper DS. The Diagnosis and Management of Thyroid Nodules: A Review [published correction appears in JAMA. 2018 Apr 17;319(15):1622. doi: 10.1001/jama.2018.3696.]. JAMA. 2018;319(9):914-924. doi:10.1001/jama.2018.0898

This study explores the use of radiofrequency ablation (RFA) or related thermal techniques for treating benign thyroid nodules. It highlights clinical outcomes, safety, and effectiveness relevant to both patients and insurance providers. Thyroid nodules are common, being detected in up to 65% of the general population. This is likely due to the increased use of diagnostic imaging for purposes unrelated to the thyroid. Most thyroid nodules are benign, clinically insignificant, and safely managed with a surveillance program. The main goal of initial and long-term follow-up is identification of the small subgroup of nodules that harbor a clinically significant cancer (≈10%), cause compressive symptoms (≈5%), or progress to functional disease (≈5%).

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