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Radiofrequency Ablation for Autonomously Functioning Thyroid Nodules: A Multicenter Study

The purpose of this study is to validate the generalizability of the efficacy and safety of radiofrequency (RF) ablation for treating autonomously functioning thyroid nodules (AFTN) in a large population multicenter study. Methods: This study included 44 patients from 5 institutions who refused or were not suitable for surgery or radioiodine therapy. Twenty-three patients were affected by a toxic nodule and 21 by a pretoxic nodule. RF ablation was performed using an 18-gauge, internally cooled electrode. Nodule volume, thyroid function, scintigraphy, symptom/cosmetic scores, and complications were evaluated before treatment and during each follow-up.

Sung, Jin & Baek, Jung & Jung, So & Kim, Ji-Hoon & Kim, Kyu & Lee, Ducky & Kim, Wonbae & Na, Dong. (2014). Radiofrequency Ablation for Autonomously Functioning Thyroid Nodules: A Multicenter Study. Thyroid : official journal of the American Thyroid Association. 25. 10.1089/thy.2014.0100.

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This multicenter study validated the efficacy and safety of RF ablation for treating AFTN; RF ablation can be considered an alternative to surgery or radioiodine therapy.

autonomously functioning thyroid nodule, thyroid, radiofrequency, laser, ethanol, hypothyroidism

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